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DNA Origami: Structures, Technology, and Applicati ons (Hardcover)
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DNA Origami: Structures, Technology, and Applicati ons (Hardcover)
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DNA ORIGAMI Discover the impact and multidisciplinary applications
of this subfield of DNA nanotechnology DNA origami refers to the
technique of assembling single-stranded DNA template molecules into
target two- and three-dimensional shapes at the nanoscale. This is
accomplished by annealing templates with hundreds of DNA strands
and then binding them through the specific base-pairing of
complementary bases. The inherent properties of these DNA
molecules--molecular recognition, self-assembly, programmability,
and structural predictability--has given rise to intriguing
applications from drug delivery systems to uses in circuitry in
plasmonic devices. The first book to examine this important
subfield, DNA Origami brings together leading experts from all
fields to explain the current state and future directions of this
cutting-edge avenue of study. The book begins by providing a
detailed examination of structural design and assembly systems and
their applications. As DNA origami technology is growing in
popularity in the disciplines of chemistry, materials science,
physics, biophysics, biology, and medicine, interdisciplinary
studies are classified and discussed in detail. In particular, the
book focuses on DNA origami used for creating new functional
materials (combining chemistry and materials science; DNA origami
for single-molecule analysis and measurements (as applied in
physics and biophysics); and DNA origami for biological detection,
diagnosis and therapeutics (medical and biological applications).
DNA Origami readers will also find: A complete guide for newcomers
that brings together fundamental and developmental aspects of DNA
origami technology Contributions by a leading team of experts that
bring expert views from different angles of the structural
developments and applications of DNA origami An emerging and
impactful research topic that will be of interest in numerous
multidisciplinary areas A helpful list of references provided at
the end of each chapter to give avenues for further study Given the
wide scope found in this groundbreaking work, DNA Origami is a
perfect resource for nanotechnologists, biologists, biophysicists,
chemists, materials scientists, medical scientists, and
pharmaceutical researchers.
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