Gadd45 Stress Sensor Genes (Hardcover, 2nd ed. 2022)

This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors. The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Advances in Experimental Medicine and Biology, 1360
Release date:	May 2022
First published:	2022
Editors:	M. Raza Zaidi • Dan A. Liebermann
Dimensions:	254 x 178mm (L x W)
Format:	Hardcover
Pages:	153
Edition:	2nd ed. 2022
ISBN-13:	978-3-03-094803-0
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Science & Mathematics > Biology, life sciences > Microbiology (non-medical) > General
LSN:	3-03-094803-X
Barcode:	9783030948030

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