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Immunoreceptor Tyrosine-based Inhibition Motifs (Hardcover)
Loot Price: R2,397
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Immunoreceptor Tyrosine-based Inhibition Motifs (Hardcover)
Series: Current Topics in Microbiology and Immunology, v.244
Expected to ship within 12 - 17 working days
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Novel molecular motifs named Immunoreceptor Tyrosine-based
Inhibition Motifs (ITIMs) have recently been recognized in the
intracytoplasmic domains of a still-increasing number of receptors
which control cell activation and proliferation. Research on
ITIM-bearing molecules has developed exponentially during the last
three years, generating new concepts with important consequences in
basic research and with exciting potential clinical applications.
The present volume contains 15 reviews written by authors who all
made significant contributions to the identification of
ITIM-bearing molecules and the study of their biological
properties. It constitutes the first synthesis ever published that
is specifically devoted to this emerging topic.
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