The volumes in this authoritative series present a
multidisciplinary approach to modeling and simulation of flows in
the cardiovascular and ventilatory systems, especially multiscale
modeling and coupled simulations. The cardiovascular and
respiratory systems are tightly coupled, as their primary function
is to supply oxygen to and remove carbon dioxide from the body's
cells. Because physiological conduits have deformable and reactive
walls, macroscopic flow behavior and prediction must be coupled to
nano- and microscopic events in a corrector scheme of regulated
mechanisms. Therefore, investigation of flows of blood and air in
physiological conduits requires an understanding of the biology,
chemistry, and physics of these systems together with the
mathematical tools to describe their functioning.
Volumes1 and 2are devoted to cell organization and fate, as well
as activities that are autoregulated and/or controlled by the cell
environment.Volume 1examined cellular features that allow
adaptation to environmental conditions.Volume 2begins with a survey
of the cell types of the nervous and endocrine systems involved in
the regulation of the vasculature and respiratory tract and growth
factors. It then describes major cell events in the circulatory and
ventilatory systems, such as cell growth, proliferation, migration,
and death. Circadian cycles that drive rhythmic gene transcription
are also covered."
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