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Calreticulin (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R2,956
Discovery Miles 29 560
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Calreticulin (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: Molecular Biology Intelligence Unit
Expected to ship within 10 - 15 working days
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This book is about calreticulin, a multifunctional calcium binding
protein first discovered over 20 years ago. The protein has been
described in various locations: endoplasmic reticulum, nuclear
envelope, cytoplasmic granules, nucleus, cell surface and even
secreted into the blood stream. This volume outlines the newly
discovered functions for calreticulin including its control of
calcium homeostasis, modulation of steroid-sensitive gene
expression, control of viral RNA replication, modulation of nuclear
transport, role in T lymphocyte activation and cytotoxic killing,
chaperone function, control of adhesion-dependent signaling via
integrins, possible role in the biology of ticks, in the pathology
of autoimmune diseases and in blood function.
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