New methods used for the detection of DNA hybridisation process,
including electrochemical, optical scattering, surface plasmon
resonance, nanogravimetric, and fluorimetric are described and
their application in assays assessing DNA damage is discussed in
this book. The analyses of damage and alterations for the DNA in
solution as well as for the DNA immobilised on core-shell gold
nanoparticles and solid electrodes are presented. These methods
enable evaluating the degree of DNA damage caused by toxicants and
can be applied to studies of the interactions of atrazine and other
herbicides and pesticides with DNA.
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