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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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The Biochemistry of Retinoid Signaling II - The Physiology of Vitamin A - Uptake, Transport, Metabolism and Signaling (Hardcover, 1st ed. 2016)
Loot Price: R7,284
Discovery Miles 72 840
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The Biochemistry of Retinoid Signaling II - The Physiology of Vitamin A - Uptake, Transport, Metabolism and Signaling (Hardcover, 1st ed. 2016)
Series: Subcellular Biochemistry, 81
Expected to ship within 10 - 15 working days
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The role of vitamin A in living organisms has been known throughout
human history. In the last 100 years, the biochemical nature of
vitamin A and its active derivative, retinoic acid, its
physiological impact on growth processes, and the essential details
of its mechanism of action have been revealed by investigations
carried out by researchers using vertebrate and more recently
invertebrate models to study a multiplicity of processes and
conditions, encompassing embryogenesis, postnatal development to
old age. A wealth of intercellular interactions, intracellular
signaling systems, and molecular mechanisms have been described and
the overall conclusion is that retinoic acid is essential for life.
This book series, with chapters authored by experts in every aspect
of this complex field, unifies the knowledge base and mechanisms
currently known in detailed, engaging, well-illustrated, focused
chapters that synthesize information for each specific area. In
view of the recent information explosion in this field, it is
timely to publish a contemporary, comprehensive, book series
recapitulating the most exciting developments in the field and
covering fundamental research in molecular mechanisms of vitamin A
action, its role in physiology, development, and continued
well-being, and the potential of vitamin A derivatives and
synthetic mimetics to serve as therapeutic treatments for cancers
and other debilitating human diseases. Volume II is divided into
nine chapters contributed by prominent experts in their respective
fields. Each chapter starts with the history of the area of
research. Then, the key findings that contributed to development of
the field are described, followed by a detailed look at key
findings and progress that are being made in current, ongoing
research. Each chapter is concluded with a discussion of the
relevance of the research and a perspective on missing pieces and
lingering gaps that the author recommends will be important in
defining future directions in vitamin A research.
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