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Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia (Paperback, Softcover reprint of the original 1st ed. 2016)
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Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia (Paperback, Softcover reprint of the original 1st ed. 2016)
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Molecular Pathogenesis and Treatment of Chronic Myelogenous
Leukemia provides a comprehensive understanding of the recent
molecular genetics of Chronic Myelogenous Leukemia (CML) and a
characterization of the molecular targets for drug development.
Included are therapeutic implications, diagnosis, and prognosis for
understanding and facilitating daily practice in the management of
patients with CML. Understanding of the pathogenesis and therapy of
hematological malignancies such as CML has grown significantly in
recent years. This development owe much to the progress in
molecular biology and now makes a major contribution to diagnosis
and to treatment that pharmacologically targets the molecular
events of CML. Molecular targeting therapy with newly developed
agents such as small molecules and antibodies for hematological
malignancies are being discovered after years of research. Some of
these, including tyrosine kinase inhibitors such as imatinib,
nilotinib, and dasatinib, lead to increased survival rates and
improved therapies. With the opinion leaders of basic and clinical
research in the field as authors, this book reviews recent advances
in the biology of CML.
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