The aspergilli are a fascinating group of fungi exhibiting immense
ecological and metabolic diversity. These include notorious
pathogens such as Aspergillus flavus, which produces aflatoxin, one
of the most potent, naturally occurring, compounds known to man.
Conversely, also included are other fungi, such as A. oryzae,
involved in the industrial production of soy sauce and sake, or A.
niger, used for the production of citric acid and enzymes, such as
glucose oxidase and lysozyme. Such is the interest in Aspergillus
that, to date, the sequences of fifteen different Aspergillus
genomes have been determined, providing scientists with an exciting
resource to improve the understanding of Aspergillus molecular
genomics and acting as a spring board for mining for new
metabolites and novel genes of industrial or medical importance. In
this book, leading Aspergillus researchers review and summarize the
most important aspects of Aspergillus molecular biology and
genomics. The book opens with a fascinating overview of the genus
Aspergillus. This is followed by in-depth reviews of: the
Aspergillus molecular systematics * comparative genomics *
bioinformatics and systems biology of Aspergillus * transcriptional
regulation * genetics and genomics of sexual development of A.
nidulans * genomics and secondary metabolism * ecology *
development and gene regulation in A. flavus * functional systems
biology * and novel industrial applications of A. oryzae genomics.
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