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Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy (Hardcover, 2012 ed.) Loot Price: R3,032
Discovery Miles 30 320
Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy (Hardcover, 2012 ed.): Matthias J. N. Junk

Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy (Hardcover, 2012 ed.)

Matthias J. N. Junk

Series: Springer Theses

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Loot Price R3,032 Discovery Miles 30 320 | Repayment Terms: R284 pm x 12*

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In his thesis, Matthias Junk takes an innovative approach to assess the local structure and dynamics of biological and synthetic amphiphilic macromolecules capable of transporting small molecules. Replacing the latter with stable radicals, he uses state-of-the-art electron paramagnetic resonance (EPR) spectroscopy to describe the highly relevant transport function from the viewpoint of the guest molecules. Such, he demonstrates that the functional structure of human serum albumin in solution significantly differs from its crystal structure - a consequence of the protein's adaptability to host various endogenous compounds and drug molecules. Further, he shows that the thermal collapse of thermoresponsive hydrogels and dendronized polymers leads to static and dynamic heterogeneities on the nanoscale. These heterogeneities bear consequences for the material's hosting properties and enable unforeseen complex catalytic functionalities.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Springer Theses
Release date: 2012
First published: 2012
Authors: Matthias J. N. Junk
Dimensions: 235 x 155 x 18mm (L x W x T)
Format: Hardcover
Pages: 212
Edition: 2012 ed.
ISBN-13: 978-3-642-25134-4
Categories: Books > Science & Mathematics > Chemistry > Physical chemistry > General
Books > Professional & Technical > Mechanical engineering & materials > Materials science > General
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LSN: 3-642-25134-X
Barcode: 9783642251344

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