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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Metal Carcinogenesis Testing - Principles and In Vitro Methods (Paperback, Softcover reprint of the original 1st ed. 1980)
Loot Price: R2,984
Discovery Miles 29 840
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Metal Carcinogenesis Testing - Principles and In Vitro Methods (Paperback, Softcover reprint of the original 1st ed. 1980)
Series: Biological Methods
Expected to ship within 10 - 15 working days
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Metal Carcinogenesis Testing explains fundamental principles of
metal carcinogenesis as they are currently understood, and provides
detailed practical descriptions of rapid and inexpensive in vitro
assay methodology presently in use for the detection of potentially
carci nogenic metals and their compounds. Mounting experimental
evidence has suggested that a number of metals and their compounds
are potentially carcinogenic to humans. Since humans are exposed to
these potentially carcinogenic metals in industrial situations and
through environmental pollution, it is essential that experimental
protocols be available to identify the specific metal compounds
that are potentially carcinogenic. This book affords a thorough
description of the various carcinogenesis test systems available
for metals, centering on those that are rapid, inexpensive, and
most reliable. The principles are discussed at the level of human
exposure, of animal studies, and of research in vitro.
Additionally, the molecular mechanisms of metal-induced cancer are
considered at each ofthese three levels.In large part, the emphasis
rests on the use of in vitro, biochemical and bacterial studies,
including tissue culture, because these methods are the basis of
the rapid and inexpensive screening of potentially carcinogenic
substances."
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