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Molecular, Cellular, and Clinical Aspects of Angiogenesis (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R2,806
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Molecular, Cellular, and Clinical Aspects of Angiogenesis (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: NATO Science Series A:, 285
Expected to ship within 10 - 15 working days
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There has been an explosion of research activity related to
angiogenesis in recent years, and hundreds of laboratories
worldwide are actively involved in many aspects of angiogenesiS.
The literature on angiogenesis increases exponentially every year,
and more than 16,000 peer-reviewed articles have been published the
past 25 years, which are scattered in basic science and clinical
journals. The complexity of the cascade of events leading to new
vessel formation from preexisting ones has challenged scientists in
cell biology, biochemistry, physiology, pharmacology, molecular
biology, developmental biology, and other fields. With their
multidisciplinary approach and the powerful new techniques that
have been developed, the progress in understanding angiogenesis has
been impressive indeed. Only 12 years ago the mention of an
angiogenic factor caused skepticism. Today we have the complete
amino-acid fiequence and their genes cloned for at least 9
angiogenic factors. Many laboratories are studying their role in
angiogenesis, and several biotechnology firms have a keen interest
in commercial developments relative to these molecules. The role of
extracellular matrix components in angiogenesis and the interaction
of endothelial cells with other cell types such as pericytes,
smooth muscle cells, and inflammatory cells have been studied by
other groups. This rapid expansion is the result of a realization
that in many disease states a common underlying pathology is a
derangement in angiogenesis.
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