In Vitamin D: Physiology, Molecular Biology, and Clinical
Applications, Second Edition, leading researchers provide a
comprehensive, highly readable overview of the biological functions
and clinical applications of vitamin D and its metabolites. Topics
range from the most recent recommendations for vitamin D intake to
new approaches for the treatment and prevention of vitamin D
deficiency and the development of active vitamin D drugs to treat
psoriasis and cancer. The book demonstrates the significant role
that vitamin D has in maintaining good bone health and the
prevention of osteoporosis, an important health problem for adults
over the age of fifty. In addition, it authoritatively reviews the
relationship between sunlight exposure, vitamin D, and increased
risk of colon and breast cancer; how vitamin D is made in the skin;
and the sequence of events that leads to its activation by the
kidney. Also examined are the biological functions of
1,25-dihydrovitamin D3 on the intestine and bone, as well as other
tissues, such as skin, the immune system, prostate, and breast, and
vitamin D's molecular mechanism of action on the cell membrane and
nucleus. The first edition of Vitamin D: Physiology, Molecular
Biology and Clinical Applications was the benchmark in the field
when published in 1999. This new and expanded volume continues to
include extensive, in-depth chapters covering the most important
aspects of the complex interactions between vitamin D and other
dietary components, the ongoing debate concerning the best
indicator of optimal vitamin D status and its nutrient
requirements, and the impact of less than optimal status on disease
risk. Vitamin D: Physiology, Molecular Biology, and Clinical
Applications, Second Edition is designed and organized not only to
be an up-to-date review on the subject, but also to provide medical
students, graduate students, health care professionals and even the
lay public with a reference source for the most up-to-date
information about the vitamin D deficiency pandemic and its
clinical implications for health and disease.
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