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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Sequence-specific DNA Binding Agents (Hardcover)
Loot Price: R4,650
Discovery Miles 46 500
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Sequence-specific DNA Binding Agents (Hardcover)
Series: RSC Biomolecular Sciences, Volume 6
Expected to ship within 12 - 17 working days
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The binding of antibiotics and drugs to DNA is a fast developing
area of research with important applications in medicine,
particularly the treatment of cancer. Sequence-specific DNA Binding
Agents uniquely discusses key aspects of this topic, providing a
novel perspective on the subject. Written by experts in the field,
this book discusses diverse modes of binding of antibiotics and
drugs to DNA, emphasising matters that are important or promising
for cancer treatment. Chapters discuss established agents like
actinomycin D but also look at novel drugs with strong potential in
chemotherapy such as new topoisomerase inhibitors, telomerase
inhibitors, peptide nucleic acids and triple helix-forming
oligonucleotides. There are also sections discussing methodological
advances including computational methods, slow kinetics, melting
curve analysis and approaches to medicinal chemistry. Finally there
is a section on RNA structure and its potential as a drug target.
The book is ideal for researchers in industry and academia who
require a comprehensive source of reference to this rapidly
expanding subject.
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