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The Black Box of Biology - A History of the Molecular Revolution (Hardcover)
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The Black Box of Biology - A History of the Molecular Revolution (Hardcover)
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In this masterful account, a historian of science surveys the
molecular biology revolution, its origin and continuing impact.
Since the 1930s, a molecular vision has been transforming biology.
Michel Morange provides an incisive and overarching history of this
transformation, from the early attempts to explain organisms by the
structure of their chemical components, to the birth and
consolidation of genetics, to the latest technologies and
discoveries enabled by the new science of life. Morange revisits A
History of Molecular Biology and offers new insights from the past
twenty years into his analysis. The Black Box of Biology shows that
what led to the incredible transformation of biology was not a
simple accumulation of new results, but the molecularization of a
large part of biology. In fact, Morange argues, the greatest
biological achievements of the past few decades should still be
understood within the molecular paradigm. What has happened is not
the displacement of molecular biology by other techniques and
avenues of research, but rather the fusion of molecular principles
and concepts with those of other disciplines, including genetics,
physics, structural chemistry, and computational biology. This has
produced decisive changes, including the discoveries of regulatory
RNAs, the development of massive scientific programs such as human
genome sequencing, and the emergence of synthetic biology, systems
biology, and epigenetics. Original, persuasive, and breathtaking in
its scope, The Black Box of Biology sets a new standard for the
history of the ongoing molecular revolution.
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