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Books > Medicine > Clinical & internal medicine > Haematology
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Hematopoietic Stem Cell Biology (Hardcover, 2010 ed.)
Loot Price: R4,041
Discovery Miles 40 410
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Hematopoietic Stem Cell Biology (Hardcover, 2010 ed.)
Series: Stem Cell Biology and Regenerative Medicine
Expected to ship within 10 - 17 working days
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In the summer of 1988, my developmental biology professor announced
to the class that hematopoietic stem cells (HSCs) had finally been
purified. Somehow, I never forgot the professor's words. When I
started working in Dr. Irv Weissman's labo- tory at Stanford as a
postdoctoral fellow, I realized that the findings mentioned by the
professor were from Weissman's laboratory and had been published in
a 1988 edition of the journal Science. It has been over 20 years
since the publication of that seminal paper, and since then
tremendous advances in understanding the biology and maturation of
HSCs, namely the process of hematopoiesis, which includes
lymphocyte development, have been made. These discoveries were made
possible in part by advancements in technology. For example, recent
availability of user friendly fluorescence activated cell sorting
(FACS) machines and monoclonal an- bodies with a variety of
fluorescent labels has allowed more scientists to sort and analyze
rare populations in the bone marrow, such as HSCs. All classes of
hematopoietic cells are derived from HSCs. Stem cell biology draws
enormous attention not only from scientists, but also from ordinary
people because of the tremendous potential for development of new
therapeutic application to diseases that currently lack any type of
effective therapy. Thus, this type of "regenerative medicine" is a
relatively new and attractive field in both basic science and
clinical medicine.
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