"Methods and Applications of Statistics in Clinical Trials,
Volume 2: Planning, Analysis, and Inferential Methods" includes
updates of established literature from the Wiley Encyclopedia of
Clinical Trials as well as original material based on the latest
developments in clinical trials. Prepared by a leading expert, the
second volume includes numerous contributions from current
prominent experts in the field of medical research. In addition,
the volume features:
- Multiple new articles exploring emerging topics, such as
evaluation methods with threshold, empirical likelihood methods,
nonparametric ROC analysis, over- and under-dispersed models, and
multi-armed bandit problems
- Up-to-date research on the Cox proportional hazard model,
frailty models, trial reports, intrarater reliability, conditional
power, and the kappa index
- Key qualitative issues including cost-effectiveness analysis,
publication bias, and regulatory issues, which are crucial to the
planning and data management of clinical trials
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