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Water Soluble Vitamins - Clinical Research and Future Application (Hardcover, 2012)
Loot Price: R6,956
Discovery Miles 69 560
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Water Soluble Vitamins - Clinical Research and Future Application (Hardcover, 2012)
Series: Subcellular Biochemistry, 56
Expected to ship within 12 - 17 working days
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The discovery of vitamins in the early 1900s, their later chemical
characterization and the clarification of pivotal metabolic
functions are sequential aspects of a brilliant chapter in the
history of modern nutritional sciences and medicine. The name,
derived from "vital-amines", indicates their elementary metabolic
key functions in human metabolism. Vitamins are truly families of
compounds, which include precursors and various free and bound
forms, all with individual roles in metabolism and function. A more
recent approach therefore searches for the components, the
understanding of their roles in physiology and pathology as well as
looking for novel pharmacological applications. When used properly,
vitamins are, indeed, "magical" substances. Due to their efficacy,
they should therefore be regarded as drugs with effects and side
effects to be weighted against each other. Today, it is not the
previously fatal deficiency-associated diseases that are in the
focus of interest, but rather the relation of suboptimal vitamin
bioavailability to chronic disease. This is complicated by genetic
susceptibility, lifestyle, and the presence or absence of
health-compromising habits, such as smoking. In turn, the
development and application of new and more sensitive and specific
assays further enable us to look more closely into the many
functions of vitamins. Water soluble vitamins are complex molecular
structures and even today, many areas in vitamin biochemistry are
not yet fully understood. Novel effects and functions of vitamins
remain and continue to be discovered. This book presents most
recent research results and fascinating new knowledge on the role
and effects of the water soluble vitamins in man. Some of the most
distinguished chemists, biochemists, biologists and clinicians have
contributed valuable chapters sharing unexpected novel insights
into the biochemistry, (epi)genetics, metabolism, and function of
water soluble vitamins, with their potential for clinical
applications. Thus, physicians, clinicians, scientists,
researchers, epidemiologists. nutritional specialists and health
professionals alike will find stimulating and fascinating new
insight in the many roles that water soluble vitamins play in human
health and disease.
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