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Books > Social sciences > Psychology > Physiological & neuro-psychology
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Circadian Clock in Brain Health and Disease (Hardcover, 1st ed. 2021)
Loot Price: R2,670
Discovery Miles 26 700
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Circadian Clock in Brain Health and Disease (Hardcover, 1st ed. 2021)
Series: Advances in Experimental Medicine and Biology, 1344
Expected to ship within 12 - 17 working days
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In this book, leading experts in the field review how circadian
rhythms impact the brain. An essential function of mammalian life
is the exploitation of the regularities provided by the 24-hour
cycle of day and night. The development and evolution of circadian
clock mechanisms have allowed us to optimally adapt our behavior
and physiology to the external world. Not surprisingly, a growing
body of evidence links the disruption of circadian rhythms by
genetic, lifestyle and environmental factors to illnesses of the
brain. In the first section of the book, readers will learn about
the molecular and anatomic architecture of circadian function in
mammals. The ways in which environmental disruptions and
misalignments can influence such mechanisms and therefore impair
brain function and health status are also addressed. In the second
part, the focus shifts to those brain regions responsible for brain
function and the body-wide regulation of circadian function.
Amongst others, special attention is paid to the role of astrocytes
and the brain's reward and hyprocretin / orexin systems. The book
concludes with an extensive discussion on the consequences of
circadian rhythm dysfunction. Several chapters present the latest
findings on Attention Deficit Hyperactivity Disorder,
schizophrenia, autism spectrum disorder, drug abuse and mood
disorders. Written by auhorities in the field, the book provides a
state-of-the-art review of the latest findings on circadian clocks
in the brain and highlights their potentially far-reaching impacts
on our health and well-being. As such, it is essential reading for
all neuroscientists and clinicians seeking to understand the
intricate connections between circadian rhythms and brain health
and illness.
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