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Viral Zoonoses and Food of Animal Origin - A Re-Evaluation of Possible Hazards for Human Health (Hardcover, 1997 ed.)
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Viral Zoonoses and Food of Animal Origin - A Re-Evaluation of Possible Hazards for Human Health (Hardcover, 1997 ed.)
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Since the central theme of this book is the transmission of disease
agents through the food chain, we will examine influenza viruses
from this perspective. Influenza A viruses are found in humans,
pigs, horses, sea mammals, and also in wild aquatic and domestic
birds 23]. How are they spread? Between mammals, influenza is an
airborne infection, but between birds, influenza can be either an
airborne or waterborne infection. Influenza viruses of aquatic
birds periodically transmit to domestic birds sometimes with
catastrophic effects; this transmis sion can be either airborne or
waterborne. Less frequently, avian influenza viruses transmit to
mammals and three to four times in the past century this
transmission has initiated a pandemic of influenza in humans. The
method of spread of avian influenza viruses to mammals remains
unresolved, but could be either airborne or waterborne. In this
report we will consider recent examples of interspecies
transmission of influenza A viruses and the possible prevention of
emergence of the next human pandemic which is considered imminent.
The reservoirs of influenza A viruses The available evidence
indicates that aquatic birds are the reservoirs of all 15 subtypes
of influenza A viruses. We will first consider the replication of
influenza A in aquatic birds. In wild ducks, influenza viruses
replicate preferentially in the cells lining the intestinal tract,
cause no disease signs, and 8 7 are excreted in high concentrations
in the feces (up to 10 ."
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