Opens the door to the sustainable production of pharmaceuticals
and fine chemicals
Driven by both public demand and government regulations,
pharmaceutical and fine chemical manufacturers are increasingly
seeking to replace stoichiometric reagents used in synthetic
transformations with catalytic routes in order to develop greener,
safer, and more cost-effective chemical processes. This book
supports the discovery, development, and implementation of new
catalytic methodologies on a process scale, opening the door to the
sustainable production of pharmaceuticals and fine chemicals.
Pairing contributions from leading academic and industrial
researchers, "Sustainable Catalysis" focuses on key areas that are
particularly important for the fine chemical and pharmaceutical
industries, including chemo-, bio-, and organo-catalytic approaches
to C-H, C-N, and C-C bond-forming reactions. Chapters include
academic overviews of current innovations and industrial case
studies at the process scale, providing new insights into green
catalytic methodologies from proof-of-concept to their applications
in the synthesis of target organic molecules.
"Sustainable Catalysis" provides the foundation needed to
develop sustainable green synthetic procedures, with coverage of
such emerging topics as: Catalytic reduction of amides avoiding
LiAlH4 or B2H6Synthesis of chiral amines using
transaminasesIndustrial applications of boric acid and boronic acid
catalyzed direct amidation reactionsC-H activation of
heteroaromaticsOrganocatalysis for asymmetric synthesis
Offering a balanced perspective on current limitations,
challenges, and solutions, "Sustainable Catalysis" is recommended
for synthetic organic chemists seeking to develop new methodologies
and for industrial chemists dedicated to large-scale process
development.
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