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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Germ Cells (Hardcover, New)
Loot Price: R2,766
Discovery Miles 27 660
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Germ Cells (Hardcover, New)
Series: Cold Spring Harbor Perspectives in Biology
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In sexually reproducing organisms, germ cells give rise to gametes
and serve as the link between generations. A key event during germ
cell development is the decision to leave mitosis and enter
meiosis, leading to the formation of mature eggs and sperm. Germ
cell development involves unique gene expression programs and the
establishment of epigenetic marks that ensure success during
fertilization and embryo development. Written and edited by experts
in the field, this collection from Cold Spring Harbor Perspectives
in Biology reviews the biology of germ cells in metazoans. The
contributors describe the undifferentiated state of germline stem
cells, the triggers for meiotic entry, and the transcriptional and
post transcriptional controls during spermatogenesis and oogenesis
that lead to the formation of mature gametes. The expression of sex
linked genes and the establishment of genomic imprinting in the
germline are also covered. This volume, which includes discussions
of gamete recognition proteins, egg activation, and genetic
reprogramming following nuclear transfer, is an indispensable
reference for cell, molecular, and developmental biologists and
anyone wishing to understand the implications of germ cell biology
for reproductive technologies.
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