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Antibody Engineering - Methods and Protocols, Second Edition (Paperback, Softcover reprint of the original 2nd ed. 2012)
Loot Price: R5,368
Discovery Miles 53 680
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Antibody Engineering - Methods and Protocols, Second Edition (Paperback, Softcover reprint of the original 2nd ed. 2012)
Series: Methods in Molecular Biology, 907
Expected to ship within 10 - 15 working days
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More than ever, antibodies are being recognized as a major drug
modality in a variety of diseases, including cancer, autoimmune
diseases, infectious diseases, or even neurodegenerative disorders.
Over 30 therapeutic antibodies have been approved and novel
molecules are entering clinical trials at an average rate of 50 per
year and that is predicted to continue well into the future.
Notwithstanding the many achievements already made in the field,
there is still a lot of room for improvements for these molecules
in terms of activity, and a plethora of approaches have been
attempted to optimize these molecules. Antibody Engineering:
Methods and Protocols, Second Edition was compiled to give complete
and easy access to a variety of antibody engineering techniques,
starting from the creation of antibody repertoires and efficient
ways to select binders from these repertoires, to their production
in various hosts, their detailed characterization using various
well established techniques, and to the modification and
optimization of these lead molecules in terms of binding activity,
specificity, size, shape, and more. Written in the successful
Methods in Molecular Biology (TM) series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
protocols, and notes on troubleshooting and avoiding known
pitfalls. Authoritative and easily accessible, Antibody
Engineering: Methods and Protocols, Second Edition serves as an
invaluable resource for both experts and those new to the field,
and most of all as a source of inspiration for the creation of the
antibodies of tomorrow.
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