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Encephalitis Lethargica - The Mind and Brain Virus (Hardcover, 1st ed. 2018)
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Encephalitis Lethargica - The Mind and Brain Virus (Hardcover, 1st ed. 2018)
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Encephalitis lethargica ('sleeping sickness') was a mysterious
disorder that swept the world in the decade following the First
World War, before disappearing without its cause having been
identified. Around 85% of its victims, predominantly children,
adolescents and younger adults, survived the acute disorder, but
most developed severe neurological syndromes, particularly severe
post-encephalitic parkinsonism and other severe motor
abnormalities, that incapacitated them for the remainder of their
lives. Despite its brief history, encephalitis lethargica played a
major role in a variety medical discussions between the two World
Wars, as this epitome of neuropsychiatric disease - attacking both
motor and mental functions - appeared just as the separation of
neurology and psychiatry had reached a critical point. Encephalitis
lethargica sufferers presented an unprecedented combination of
neurologic and psychiatric symptoms - including previously puzzling
phenomena primarily associated with schizophrenia and hysteria, as
well as behavioral changes and attention deficit disorders in
children - that not only underscored the unity of mind and movement
in the CNS, but also illuminated the critical role played by
subcortical structures in consciousness and other higher mental
functions that had formerly been associated with the soul and more
recently presumed to be localized to the human cerebral cortex.
Encephalitis lethargica exerted a greater influence on clinical and
theoretic neuroscientific thought between the two World Wars than
any other single disorder and had an enduring impact upon neurology
and psychiatry. This book will be of interest to an educated
audience active or interested in clinical (neurology, psychiatry,
psychology) or laboratory neuroscience, particularly those
interested in neuropsychiatry, as well as to those interested in
the history of the biomedical sciences.
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