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Books > Science & Mathematics > Biology, life sciences > Biochemistry
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Cytochrome P450 - Structure, Mechanism, and Biochemistry (Hardcover, 4th ed. 2015)
Loot Price: R11,515
Discovery Miles 115 150
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Cytochrome P450 - Structure, Mechanism, and Biochemistry (Hardcover, 4th ed. 2015)
Expected to ship within 10 - 15 working days
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This authoritative Fourth Edition summarizes the advances of the
past decade concerning the structure, mechanism, and biochemistry
of cytochrome P450 enzymes, with sufficient coverage of earlier
work to make each chapter a comprehensive review of the field.
Thirteen chapters are divided into two detailed volumes, the first
covering the fundamentals of cytochrome P450 biochemistry, as well
as the microbial, plant, and insect systems, and the second
exclusively focusing on mammalian systems. Volume 1 begins with an
exploration of the biophysics and mechanistic enzymology of
cytochrome P450 enzymes, with a discussion of the structures of
P450 enzymes and their electron donor partners, the mechanisms of
oxygen activation and substrate oxidation, and the approaches and
nature of cytochrome P450 inhibition. Two more chapters discuss the
nature and roles of cytochrome P450 enzymes in microbes, plants and
insects, and an eighth chapter is a survey of the potential utility
of P450 enzymes in biotechnology. The first chapter of Volume 2
examines the roles of P450 enzymes in mammals, mainly humans. Four
further chapters then deal with the genetic and hormonal regulation
of P450 enzymes and their specific roles in the processing of
sterols and lipids. Cytochrome P450: Structure, Mechanism, and
Biochemistry is a key resource for scientists, professors, and
students interested in fields as diverse as biochemistry,
chemistry, biophysics, molecular biology, pharmacology and
toxicology.
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