In this unique overview of the Hsp60 chaperonin, Peter Bross
addresses molecular biologists, medical research scientists and
individuals interested in molecular or general biology. First,
Bross discusses the basics of the Hsp60 chaperonin in terms of its
structure and the molecular mechanisms determining its function.
Second, the author highlights the multiple roles of Hsp60 for
cellular systems and regulatory pathways, especially in connection
with neurodegenerative diseases caused by Hsp60 deficiency.
Finally, the author highlights controversial observations
suggesting additional, non-standard functions of Hsp60 in and
outside mitochondria as well as possible gaps in our understanding
of the chaperonin. This volume serves as a snapshot suitable for
experienced researcher working in fields related to molecular
chaperones yet still accessible to researchers entering the field.
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