One of the most exciting aspects of marine biotechnology is
bioprospecting: the search for new natural compounds that can be
used as novel pharmaceuticals, healthcare products, agrichemicals
for crop protection, and novel bioremediation agents for
environmental protection. A new marine-derived analgesic drug,
ziconotide (trade name "prialt"), was recently licensed in the USA
and other drugs, currently in the late stages of clinical trials,
are likely to follow soon. This has fuelled enormous interest in
marine biotechnology.
This book critically reviews the most innovative strategies to
exploit the full potential of many novel natural compounds, to
understand their complex structures and to increase their inherent
low yields. The authors discuss the genetics and molecular biology
of the bioactive compound biosynthesis, the identification of the
organisms involved and the methodologies for sustainable product
production.
General
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