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Aquareovirus (Hardcover, 1st ed. 2021)
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Aquareovirus (Hardcover, 1st ed. 2021)
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Aquareoviruses cause infection in bony fish and shellfish and thus,
constitute a significant threat to aquaculture industries
worldwide. Aquareoviruses, belonging to the family Reoviridae, have
genomes consisting of 11 segments of double-stranded RNA contained
within a core (T = 1) surrounded by a double-layered icosahedral
capsid with a T = 13 symmetry in general. These viruses not only
physically resemble mammalian orthoreoviruses, but also show the
highest amino acid identity. More than hundred aquareoviruses have
been isolated from both saline water and freshwater origins;
however, literary sources elucidating aquareovirus biology are very
limited. Given the increasing pace of discovery, it is imperative
to make a clear, systematic filing of key aspects of
aquareoviruses. Therefore, the aim of writing this book is to
provide insights into the molecular mechanisms of evolution,
pathogenesis, and host response in aquareovirus infection. This
book offers a state-of-the-art report on recent discoveries
concerning the aquareovirus genome evolution, gene encoded protein
functions, and pathogenesis by comparison with its sister genus
Orthoreovirus, including avian and mammalian reoviruses. It mainly
focuses on advances made over the past 30 years in research on the
general and molecular biology, protein structure and function,
infection and replication, epidemiology and diagnosis,
immunological prevention and medical treatment, and host antiviral
immunity against aquareovirus infection. This book will help
curious graduate students or interested researchers acquire an
overall picture of aquareovirus infection and pathogenesis, as well
as yield benefits in fisheries to better prevent and control
diseases caused by aquareovirus infection.
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