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Molecular Neurovirology - Pathogenesis of Viral CNS Infections (Hardcover, 1992 ed.)
Loot Price: R4,510
Discovery Miles 45 100
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Molecular Neurovirology - Pathogenesis of Viral CNS Infections (Hardcover, 1992 ed.)
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Neurovirology, the study of viral infection of the ner vous system,
has evolved at the interface of three of the most rapidly unfolding
fields of investigation-neurobiology, vi rology, and immunology. In
all three, increasing knowledge about the molecular structure of
surface receptors, how in tracellular messages are transmitted, and
how diversity is regulated genetically is provided, along with the
techniques of molecular biology. This promises to give us knowledge
not only about the process of infection and the complex host and
viral determinants of neuroinvasiveness and neurovirulence, but
eventually it will provide the background from which to engineer
vaccines and to devise novel therapeutic agents. Animal virology
and molecular biology developed quite independently from different
origins. Animal virology was originally the province of the
pathologists, and by clinical observation and histological
preparations, they tried to ex plain the incubation period, the
pathways of virus spread, and the mechanisms of disease. Molecular
virology grew out of biochemistry, particularly through studies of
bacterio phage, with emphasis on the physical and chemical
structure of viruses and the sequences of biochemical events during
the replicative cycle in cells."
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