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Chronic Myeloid Neoplasias and Clonal Overlap Syndromes - Epidemiology, Pathophysiology and Treatment Options (Paperback, Softcover reprint of the original 1st ed. 2010)
Loot Price: R6,271
Discovery Miles 62 710
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Chronic Myeloid Neoplasias and Clonal Overlap Syndromes - Epidemiology, Pathophysiology and Treatment Options (Paperback, Softcover reprint of the original 1st ed. 2010)
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Introduction The understanding of the genetic, epigenetic, immuno-
well as for practicing hematologists or oncologists. logical and
biological causes of myeloproliferative dis- Each chapter follows a
similar architecture and leads orders has substantially improved in
the last few years. through epidemiology, genetic and molecular
causes, Together with refined tools in pathology, the successful
hematological and clinical findings, prognostic factors
establishment of mouse models mimicking at least some and current
treatment approaches of the diseases. of the myeloproliferative
disorders, and murine models Effort has been made to point out the
evolving field of novel drugs in this arena but simultaneously
diff- allowing to carefully dissect the role of mutations and gene
dosage effects of, for example JAK2, this has led to entiate
between standard and experimental treatment ever increasing numbers
of modified classification approaches. schemes. It is therefore
important for the heamtologist Together with the co-editors and all
the authors of or oncologist to keep up with this rapid change in
classi- the various chapters I hope that the readers of the book
fication language, the upcoming of new entities or differ- will
enjoy reading and benefit from the information entiation between,
or subclassification of, rare diseases provided.
General
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