"Translational Neuroimaging: Tools for CNS Drug Discovery,
Development and Treatment" combines the experience of academic,
clinical and industrial neuroimagers in a unique collaborative
approach to provide an integrated perspective of the use of small
animal and human brain imaging in developing and validating
translational models and biomarkers for the study and treatment of
neuropsychiatric disorders. "Translational Neuroimaging: Tools for
CNS Drug Discovery, Development and Treatment" examines the
translational role of neuroimaging in model development from
preclinical animal models, to human experimental medicine, and
finally to clinical studies. The focus of this book is to identify
and provide common endpoints between species that can serve to
inform both the clinic and the bench with the information needed to
accelerate clinically-effective CNS drug discovery. This book
covers methodical issues in human and animal neuroimaging
translational research as well as detailed applied examples of the
use of neuroimaging in neuropsychiatric disorders and the
development of drugs for their treatment. Offering an accompanying
website with illustrations and text available for further knowledge
and presentations, "Translational Neuroimaging: Tools for CNS Drug
Discovery, Development and Treatment" appeals to non-clinical and
clinical neuroscientists working in and studying neuropsychiatric
disorders and their treatment as well as providing the novice
researcher or researcher outside of his/her expertise the
opportunity to understand the background of translational research
and the use of imaging in this field.
Provides a background to translational research and the use of
brain imaging in neuropsychiatric disordersCritical discussion of
the potential and limitations of neuroimaging as a translational
tool for identifying and validating biomarkersIdentifies cross
species neurosystems and common endpoints necessary to help
accelerate CNS drug discovery and development for the treatment of
neuropsychiatric disordersFeatures an accompanying website with
additional images and text
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