A comprehensive collection of classic and innovative methodologies
used in many laboratories for the investigation of multiple
myeloma. These readily reproducible techniques range from the
standard Plasma Cell Labeling Index methodology to a final chapter
on making sense of microarrays, and include the full spectrum of
cytogenetic and molecular diagnostic methods. The protocols follow
the successful Methods in Molecular Medicine (TM) series format,
each offering step-by-step laboratory instructions, an introduction
outlining the principle behind the technique, lists of the
necessary equipment and reagents, and tips on troubleshooting and
avoiding known pitfalls. These proven techniques are ideal for
studying the pathogenesis of multiple myeloma and identifying new
therapeutic targets.
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