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Methodological Assessments of DSD - Special Topic Issue: Sexual Development 2018, Vol. 12, No. 1-3 (Paperback)
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Methodological Assessments of DSD - Special Topic Issue: Sexual Development 2018, Vol. 12, No. 1-3 (Paperback)
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In the rapidly expanding research and clinical field of disorders
of sex development (DSD), this publication is dedicated to the
methodological assessment of DSD based on extensive review of the
development of laboratory investigations. Starting with reports on
the role of copy number variants, testicular protein hormones and
the traditional hCG test in the assessment of DSD, the publication
goes on to cover the 'hot' topic which is the reference values for
gonadal and adrenal hormones from birth to adulthood. The imaging
techniques, endoscopy, laparoscopy as well as the pathology of the
germ cell cancer, including the 'genvironment' hypothesis, are
elaborated. Considering the increasing importance of the holistic
care of individuals with DSD, the publication provides guidance for
psychological evaluation in the field, and gives a thorough
overview of the opportunities offered by the recent European
Reference Network for Rare Endocrine Disorders (Endo-ERN) to ensure
equal access to high quality care for all those affected by DSD.
The publication concludes with a discussion on the transposition of
advanced research knowledge in daily practice on the basis of the
EuroDSD network. This publication will be essential reading for all
clinicians who are involved in delivering health care to patients
with a DSD as well as for scientists involved in biomedical
research related to DSD.
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