Apoptosis, or programmed cell death, is an adaptive form of cell
death that plays a critical role in turnover of mitotic cells and
various tissues in the adult, including epithelial cells,
fibroblasts and various endocrine cells. Programmed cell death also
plays a major role in development in organizing the body plan and
molding intricate cellular structures such as nerve cell circuits
in the brain. Rapidly progressing research into the molecular and
biochemical underpinnings of the programmed cell death process are
revealing novel genetic programs and molecular interactions that
coordinate a process that results in death and removal of cells
without an immune response and in the absence of the adverse
effects on neighboring cells.
"Programmed Cell Death, Volume I," critically details the
molecular, biochemical and cellular mechanisms of apoptosis. This
volume covers programmed cell death in a variety of tissues and
organ systems highlighting the interesting families of proteins
involved in promoting or preventing apoptosis. These include the
caspase and calpain families of proteases, Bcl-2 family members,
and inhibitors of apoptosis proteins. Each chapter is written by an
internationally recognized expert in a particular aspect of
programmed cell death.
This book will provide the reader with a comprehensive
understanding of the cascade of events leading from an apoptotic
signal, such as trophic factor withdrawal or increased oxidative
stress, to cell death. Importantly, this volume also covers
signaling mechanisms designed to prevent apoptosis. Such
anti-apoptotic signaling cascades involve neurotrophic factors and
stress response pathways. "Programmed Cell Death, Volume I,"
provides the molecular and cellular foundation for http:
//www.elsevier.com/locate/isbn/0444507302Programmed Cell Death,
Volume II in which the roles of aberrant regulation of apoptosis in
human diseases ranging from cancer to Alzheimer's disease are
considered.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
