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Microvascular Corrosion Casting in Scanning Electron Microscopy - Techniques and Applications (Paperback, Softcover reprint of the original 1st ed. 1992)
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Microvascular Corrosion Casting in Scanning Electron Microscopy - Techniques and Applications (Paperback, Softcover reprint of the original 1st ed. 1992)
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Several methods have been used to demonstrate the vasculature of
different organs in man and other species. Many attempts to
evaluate the precise microangioarchitecture of organ systems
remained unproductive, others were controversial. The development
of electron microscope in thirties opend new perspectives in
researching microvascular systems. Transmission electron microscopy
provided a two-dimensional view on microcirculatory system at
higher magnifications, however, its standardization was delayed
unnecessarily. The use of methyl methacrylate and related compounds
for obtaining replicas of vascular beds, and their study in
scanning electron microscope opened a new window in
micromorphological research. For the first time, a
three-dimensional image analysis of the vascular system was
possible. The microvascular corrosion casting method has meanwhile
attracted the interest of many contemporary scientists. Its
application to medical and biological problems justify it to be
used as a routine method for microvascular investigations. The
first investigators who used this method, focused either on
methodological details or they dealt with the normal microanatomy
of organs. The advantages of this method in demonstrating
pathological microvascular patterns are also evident.
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