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Polymeric nanoparticles for the treatment of solid tumors (Hardcover, 1st ed. 2022)
Loot Price: R5,316
Discovery Miles 53 160
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Polymeric nanoparticles for the treatment of solid tumors (Hardcover, 1st ed. 2022)
Series: Environmental Chemistry for a Sustainable World, 71
Expected to ship within 10 - 15 working days
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This book focuses on the emerging research in the field of
treatment of solid tumors or cancer with new drug delivery systems
using nanotechnology. Nanotechnology has given us a good scope for
development of new innovative drug delivery strategies to increase
the therapeutic efficacy of anticancer drugs with reduced
off-target side effects. Cancer is one of the main causes of death
worldwide due to the limitations of classical therapies such as low
solubility of active drugs, toxic side effects on healthy cells and
resistance of tumor cells. These issues are partly solved by the
recent development of polymeric nanoparticles, which improve drug
absorption and the therapeutic index, while reducing side effects.
Drug carriers must be biocompatible, biodegradable and
non-immunogenic. Coupled to a ligand that has affinity for that
particular cell, polymeric nanoparticles are used to target
specifically malignant cells or tissues and, in turn, improve drug
stability. This book presents the latest advances in the
application of polymeric particles for cancer treatment, with focus
on the tumor microenvironment, synthesis, active and passive
targeting, patents, targeting over-expressed receptors,
tumor-targeting ligands, theranostics, glioblastoma tumors, lung
cancer, breast cancer, prostate cancer and pH-responsive
nanoparticles
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