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Protein Engineering and Design (Hardcover)
Loot Price: R5,820
Discovery Miles 58 200
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Protein Engineering and Design (Hardcover)
Expected to ship within 12 - 19 working days
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Experimental protein engineering and computational protein design
are broad but complementary strategies for developing proteins with
altered or novel structural properties and biological functions. By
describing cutting-edge advances in both of these fields, Protein
Engineering and Design aims to cultivate a synergistic approach to
protein science. Experimental Protein Engineering The first half of
the book discusses experimental approaches to protein engineering
and starts by describing several high-throughput screening
platforms for protein engineering. Key techniques used for
diversity generation are also discussed. The next few chapters
present examples of therapeutics, enzymes, biomaterials, and other
proteins that have been engineered by rational or combinatorial
approaches. The section finishes with a chapter on the use of
non-natural amino acids in protein engineering. Computational
Protein Design The second half of the book introduces computational
protein design, beginning with a chapter on computational and
informatics algorithms used in protein engineering. Core components
of computational protein design are then discussed in detail, and
examples of heuristic protein design are provided. Subsequent
chapters present examples of how computational design has played a
critical role in advancing the field of protein engineering.
Concluding with a chapter outlining current challenges in the
field, this book makes computational protein design and
diversity-oriented protein engineering widely accessible to a broad
audience in academia and industry alike.
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