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Frontiers of Biostatistical Methods and Applications in Clinical Oncology (Hardcover, 1st ed. 2017)
Loot Price: R3,143
Discovery Miles 31 430
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Frontiers of Biostatistical Methods and Applications in Clinical Oncology (Hardcover, 1st ed. 2017)
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This book presents the state of the art of biostatistical methods
and their applications in clinical oncology. Many methodologies
established today in biostatistics have been brought about through
its applications to the design and analysis of oncology clinical
studies. This field of oncology, now in the midst of evolution
owing to rapid advances in biotechnologies and cancer genomics, is
becoming one of the most promising disease fields in the shift
toward personalized medicine. Modern developments of diagnosis and
therapeutics of cancer have also been continuously fueled by recent
progress in establishing the infrastructure for conducting more
complex, large-scale clinical trials and observational studies. The
field of cancer clinical studies therefore will continue to provide
many new statistical challenges that warrant further progress in
the methodology and practice of biostatistics. This book provides a
systematic coverage of various stages of cancer clinical studies.
Topics from modern cancer clinical trials include phase I clinical
trials for combination therapies, exploratory phase II trials with
multiple endpoints/treatments, and confirmative biomarker-based
phase III trials with interim monitoring and adaptation. It also
covers important areas of cancer screening, prognostic analysis,
and the analysis of large-scale molecular data in the era of big
data.
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