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Insight on Genotoxicity (Hardcover)
Loot Price: R3,257
Discovery Miles 32 570
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Insight on Genotoxicity (Hardcover)
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Genetic toxicology is considered to be an important assessment tool
as there is genetic impact of artificial chemicals. Insight on
Genotoxicity discusses testing, mechanism, prediction, and
bioindicator of genotoxicity taking into consideration recent
advances in nano-engineered particles. Corollary of DNA dent is
also discussed in detail taking into consideration the impact of
ICH guidelines on genotoxicity testing, which is important for drug
discovery innovation and development. Perspective review of
genotoxicity evaluation in phytopharmaceuticals has been mentioned
along with the prevention of genotoxicity in brief viewpoint.
Salient Features Presents methods, standard protocols, and
guidelines for genotoxicity testing Examines the impact of ICH
Guidelines on genetic toxicity testing which is a regulatory
requirement for drug discovery and development Defines appropriate
strategies about advances in in vivo genotoxicity testing which
have been listed along with progress and prospects Discusses
advancement in the high-throughput approaches for genotoxicity
testing Details computational prediction of genotoxicity with
consideration of mutagenicity, chromosomal damage caused and
strategies for computational prediction in drug development
General
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