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Books > Medicine > Clinical & internal medicine > Haematology
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Behcets Disease - Progress in Recent Years & Unmet Needs for the Future (Hardcover)
Loot Price: R5,532
Discovery Miles 55 320
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Behcets Disease - Progress in Recent Years & Unmet Needs for the Future (Hardcover)
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Behcet's disease is a chronic relapsing inflammatory disease of
unknown etiology involving multiple organs. Along with blindness,
other bodily functions are greatly affected by this disease;
conditions of the vascular, intestinal and central nervous systems
are usually life threatening and require aggressive therapy.
Recently, significant progress has been made in several areas of
this disease. The introduction of biological agents (such as
anti-TNF) have had a positive impact on the effectiveness of
treatments. However, there are still a number of unmet needs in
various fields of this disease. Despite this, there remains a
number of unaddressed issues concerning the treatments of this
disease. Several genes have been shown to be associated with this
disease, in addition to HLA-B51. Abnormalities in several subsets
of T helper cells have been implicated in the pathogenesis of
Behcet's disease. Recent advances in the field of innate immunity
have shed light on the new aspects of Behcet's disease; that is,
this disease has both autoimmunity and autoinflammatory aspects. On
the other hand, there are still controversies as to the diagnosis
and treatment of recalcitrant manifestations of the disease. This
publication highlights the most recent understanding of Behcet's
disease and raises several unanswered questions in both basic to
clinical treatment of this ailment. The contents of this book are
primarily based on the most up-to-date results of research programs
sponsored by the Japanese government as well as findings from
Korean researchers. In particular, novel classification for
neurological involvement (which has been discovered in Japan) led
to the establishment of diagnostic criteria and treatment
recommendation. Thus, this publication brings forth useful
information for a variety of specialists who are involved in the
management of this intractable disease.
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