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Sequence Data Analysis Guidebook (Hardcover, 1997 ed.)
Loot Price: R4,559
Discovery Miles 45 590
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Sequence Data Analysis Guidebook (Hardcover, 1997 ed.)
Series: Methods in Molecular Biology, 70
Expected to ship within 12 - 17 working days
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Total price: R4,579
Discovery Miles: 45 790
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Computers have revolutionized the analysis of sequencing data. It
is unlikely that any sequencing projects have been performed in the
last few years without the aid of computers. Recently their role
has taken a further major step forward. Computers have become
smaller and more powerful and the software has become simpler to
use as it has grown in sophistication. This book reflects that
change since the majority of packages described here are designed
to be used on desktop computers. Computer software is now available
that can run gels, collect data, and assess its accuracy. It can
assemble, align, or compare multiple fragments, perform restriction
analyses, identify coding regions and specific motifs, and even
design the primers needed to extend the sequencing. Much of this
soft ware may now be used on relatively inexpensive computers. It
is now possible to progress from isolate d DNA to database
submission without writing a single base down. To reflect this
progression, the chapters in our Sequence Data Analysis Guidebook
are arranged, not by software package, but by fimction. The early
chapters deal with examining the data produced by modem automated
sequenc ers, assessing its quality, and removing extraneous data.
The following chap ters describe the process of aligning multiple
sequences in order to assemble overlapping fragments into sequence
contigs to compare similar sequences from different sources.
Subsequent chapters describe procedures for compar ing the newly
derived sequence to the massive amounts of information in the
sequence databases."
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