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Mass Spectrometry Imaging - Principles and Protocols (Hardcover, 2010)
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Mass Spectrometry Imaging - Principles and Protocols (Hardcover, 2010)
Series: Methods in Molecular Biology, 656
Expected to ship within 10 - 15 working days
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Mass spectrometry (MS) offers unmatched capabilities for the
detection, characterization, and identification of a broad range of
analytes. Mass spectrometry imaging (MSI) integrates MS data with
information on the spatial distributions of the analytes, further
enhancing the applicability of MS. In Mass Spectrometry Imaging:
Principles and Protocols, expert practitioners from academia,
industry, and the clinic contribute cutting-edge protocols
describing the application of MSI to investigations of analyte
localization in a variety of specimens, from microorganisms to
plant and animal tissues. Divided into three sections, this volume
presents the principles of MS, current and future trends of MSI,
and qualitative and quantitative protocols to measure and identify
endogenous metabolites and xenobiotics. An array of MSI approaches
and technologies for characterizing peptide and protein
distributions are described in detail. Written in the highly
successful Methods in Molecular Biology (TM) series format,
protocol chapters include introductions to their respective topics,
lists of the necessary materials and reagents, and step-by-step,
readily reproducible laboratory procedures. Also included are notes
providing tips to avoid experimental pitfalls and helpful
suggestions for method troubleshooting. Comprehensive and
up-to-date, Mass Spectrometry Imaging: Principles and Protocols is
written for scientists, biological and chemical engineers, and
clinicians who are interested in applying MSI in their work and
those who would benefit from having detailed experimental
guidelines available in a single, convenient source.
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