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Reordering Life - Knowledge and Control in the Genomics Revolution (Hardcover)
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Reordering Life - Knowledge and Control in the Genomics Revolution (Hardcover)
Series: Inside Technology
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How the regimes governing biological research changed during the
genomics revolution, focusing on the Human Genome Project. The rise
of genomics engendered intense struggle over the control of
knowledge. In Reordering Life, Stephen Hilgartner examines the
"genomics revolution" and develops a novel approach to studying the
dynamics of change in knowledge and control. Hilgartner focuses on
the Human Genome Project (HGP)-the symbolic and scientific
centerpiece of the emerging field-showing how problems of
governance arose in concert with new knowledge and technology.
Using a theoretical framework that analyzes "knowledge control
regimes," Hilgartner investigates change in how control was
secured, contested, allocated, resisted, justified, and reshaped as
biological knowledge was transformed. Beyond illuminating genomics,
Reordering Life sheds new light on broader issues about secrecy and
openness in science, data access and ownership, and the politics of
research communities. Drawing on real-time interviews and
observations made during the HGP, Reordering Life describes the
sociotechnical challenges and contentious issues that the genomics
community faced throughout the project. Hilgartner analyzes how
laboratories control access to data, biomaterials, plans,
preliminary results, and rumors; compares conflicting visions of
how to impose coordinating mechanisms; examines the repeated
destabilization and restabilization of the regimes governing genome
databases; and examines the fierce competition between the publicly
funded HGP and the private company Celera Genomics. The result is
at once a path-breaking study of a self-consciously revolutionary
science, and a provocative analysis of how knowledge and control
are reconfigured during transformative scientific change.
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