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Books > Medicine > General issues > Public health & preventive medicine > Epidemiology & medical statistics
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Sample Sizes for Clinical Trials (Hardcover, 2nd edition)
Loot Price: R3,059
Discovery Miles 30 590
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Sample Sizes for Clinical Trials (Hardcover, 2nd edition)
Expected to ship within 9 - 15 working days
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Sample Sizes for Clinical Trials, Second Edition is a practical
book that assists researchers in their estimation of the sample
size for clinical trials. Throughout the book there are detailed
worked examples to illustrate both how to do the calculations and
how to present them to colleagues or in protocols. The book also
highlights some of the pitfalls in calculations as well as the key
steps that lead to the final sample size calculation. Features:
Comprehensive coverage of sample size calculations, including
Normal, binary, ordinal, and survival outcome data Covers
superiority, equivalence, non-inferiority, bioequivalence and
precision objectives for both parallel group and crossover designs
Highlights how trial objectives impact the study design with
respect to both the derivation of sample formulae and the size of
the study Motivated with examples of real-life clinical trials
showing how the calculations can be applied New edition is extended
with all chapters revised, some substantially, and four completely
new chapters on multiplicity, cluster trials, pilot studies, and
single arm trials The book is primarily aimed at researchers and
practitioners of clinical trials and biostatistics, and could be
used to teach a course on sample size calculations. The importance
of a sample size calculation when designing a clinical trial is
highlighted in the book. It enables readers to quickly find an
appropriate sample size formula, with an associated worked example,
complemented by tables to assist in the calculations.
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