Contents:
OVERVIEW
Lewis, D.A. and Lieberman, J.A. 'Catching Up on Schizophrenia, Natural History and Neurobiology.'Neuron 28 (2000).
EPIDEMIOLOGY
Kendler, K., Gallagher, T., Abelson, J., and Kessler, R.C. 'Lifetime Prevalence, Demographic Risk Factors, and Diagnostic Validity of Nonaffective Psychosis as Assessed in a US Community Sample.'Archives of General Psychiatry 53 (1996).
Mortensen, P.B., Pedersen, C.B., Westergaard, T., Wohlfahrt, J., Ewald, H., Mors, O., Andersen, P.K., and Melbye, M. 'Effects of Family History and Place and Season of Birth on the Risk of Schizophrenia.' New England Journal of Medicine 340 (1999).
GENETICS
Riley, B.P. and McGuffin, P. 'Linkage and Association Studies of Schizophrenia.' American Journal of Medical Genetics 97 (2000).
Baron, M. 'Genetics of Schizophrenia and the New Millenium: Progress and Pitfalls.' American Journal of Human Genetics 68 (2001).
Kety, S.S., Rosenthal, D., Wender, P.H., and Schulsinger, F. 'Mental Illness in the Biological and Adoptive Familes of Adopted Schizophrenics.' American Journal of Psychiatry 128 (1971)
NATURAL HISTORY
Bromet, E.J. and Fennig, S. 'Epidemiology and Natural History of Schizophrenia.' Biological Psychiatry 46 (1999).
Hearton, R.K., Gladsjo, J.A., Palmer, B.W., Kuck, J., Marcotte, T.D., and Jeste, D.V. 'Stability and Course of Neuropsychological Deficits in Schizophrenia.' Archives of General Psychiatry 58 (2001)
Robinson, D., Woerner, M.G., Alvir, J.M., Bilder, R., Goldman, R., Geisler, S., Koreen, A., Sheitman, B., Chakos, M., Mayerhoff, D., and Lieberman, J.A. 'Predictors of Relapse Following Response From a First Episode of Schizophrenia or Schizoaffective Disorder.' Archives of General Psychiatry 56 (1999).
NEUROBIOLOGY OF DISEASE
Akil, M., Pierri, J.N., Whitehead, R.E., Edgar, C.L., Mohila, C., Sampson, A.R, and Lewis, D.A. 'Lamina-Specific Alterations in the Dopamine Innervation of the Prefrontal Cortex in Schizophrenic Subjects.' American Journal of Psychiatry 156 (1999).
Arnold, S.E., Trojanowski, J.Q., Gur, R.E., Blackwell, P., Han, L.Y., and Choi, C. 'Absence of Neurodegeneration and Neural Injury in the Cerebral Cortex in a Sample of Elderly Patients with Schizophrenia.' Archives of General Psychiatry 55 (1998)
Braver, T.S., Barch, D.M., and Cohen, J.D., 'Cognition and Control in Schizophrenia: A Computational Model of Dopamine and Prefrontal Function.' Biological Psychiatry 46 (1999).
Glantz, L.A. and Lewis, D.A. 'Decreased Dendritic Spine Density on Prefrontal Cortical Pyramidal Neurons in Schizophrenia.' Archives of General Psychiatry 57 (2000).
Laruelle, M., Abi-Dargham, A., van Dyck, C.H., Gil, R., D'Souza, C.D., Erdos, J., McCance, E., Rosenblatt, W., Fingado, C., Zoghbi, S.S., Baldwin, R.M., Seibyl, J.P., Krystal, J.H., Charney, D.S., and Innis R.B., 'Single Photon Emission Computerized Tomography Imaging of Amphetamine-Induced Dopamine Release in Drug-Free Schizophrenic Subjects.' Proceedings of the National Academy of Sciences of the USA 93 (1996).
Okubo, Y., Suhara, T., Suzuki, K., Kobayashi, K., Inoue, O., Terasaki, O., Someya, Y., Sassa, T., Sudo, Y., Matsushima, E., Iyo, M., Tateno, Y., and Toru, M. 'Decreased Prefrontal Dopamine D1 Receptors in Schizophrenia Revealed by PET.' Nature 385 (1997).
Rajkowska, G., Selemon, L.D., and Goldman-Rakic, P.S. 'Neuronal and Glial Somal Size in the Prefrontal Cortex: A Postmortem Morphometric Study of Schizophrenia and Huntingdon Disease.' Archives of General Psychiatry 55 (1998).
Rapoport, J.L., Giedd, J.N., Blumenthal, J., Hamburger, S., Jeffries, N., Fernandez, T., Nicholson, R., Bedwell, J., Lenane, M., Zijdenbos, A., Paus, T., and Evans, A. 'Progressive Cortical Change During Adolescence in Childhood-Onset Schizophrenia. A Longitudinal Magnetic Resonance Imaging Study.' Archives of General Psychiatry 56 (1999).
Selemon, L.D. and Goldman-Rakic, P.S. 'The Reduced Neuropil Hypothesis: A Circuit Based Model of Schizophrenia.' Biological Psychiatry 45 (1999).
Suddath, R.L., Christison, G.W., Torrey, E.F., Casanova, M.F., and Weinberger, D.R. 'Anatomical Abnormalities in the Brains of Monozygotic Twins Discordant for Schizophrenia.' New England Journal of Medicine 322 (1990).
Weinberger, D.R. 'Implications of Normal Brain Development for the Pathogenesis of Schizophrenia.' Archives of General Psychiatry 44 (1987).
TREATMENT
Bustillo, J.R., Lauriello, J., Horan, W.P., and Keith, S.J. 'The Psychosocial Treatment of Schizophrenia: An Update.' American Journal of Psychiatry 158 (2001).
Castner, S.A., Williams, G.V., and Goldman-Rakic, P.S. 'Reversal of Antipsychotic-Induced Working Memory Deficits by Short-Term Dopamine D1 Receptor Stimulation.' Science 287 (2000).
Kapur, S., Zipursky, R.B., Remington, G. 'Clinical and Theoretical Implications of 5HT2 and D2 Receptor Occupancy of Clozapine, Risperidone, and Olanzapine in Schizophrenia.' American Journal of Psychiatry 156 (1999).
Lidow, M.S., Song, Z.-M., Castner, S.A., Allen, P.B., Greengard, P., and Goldman-Rakic, P.S. 'Antipsychotic Treatment Induces Alterations in Dendrite and Spine Associated Proteins in Dopamine-Rich Areas of the Primate Cerebral Cortex.' Biological Psychiatry 49 (2001).
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