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Mechanisms of Lymphocyte Activation and Immune Regulation, v. 4 - Cellular Communications - Proceedings of an International Conference Held in Newport Beach, California, February 14-16, 1992 (Hardcover) Loot Price: R2,596
Discovery Miles 25 960
Mechanisms of Lymphocyte Activation and Immune Regulation, v. 4 - Cellular Communications - Proceedings of an International...

Mechanisms of Lymphocyte Activation and Immune Regulation, v. 4 - Cellular Communications - Proceedings of an International Conference Held in Newport Beach, California, February 14-16, 1992 (Hardcover)

Sudhir Gupta, Thomas A. Waldmann

Series: Advances in Experimental Medicine and Biology, v. 323

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Loot Price R2,596 Discovery Miles 25 960 | Repayment Terms: R243 pm x 12*

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Section I: T Cell Receptors and T Cell Activation.- T Cell Receptor Structure and Function: Analysis by Expression of Portions of Isolated Subunits.- The T Cell Antigen Receptor Tyrosine Kinase Pathway.- Dissection of the Hb(64-76) Determinant Reveals That the T Cell Receptor May Have the Capacity to Differentially Signal.- CD28 Receptor Crosslinking Induces Tyrosine Phosphorylation of PLC?1.- Structure and Function of CD45: A Leukocyte-Specific Protein Tyrosine Phosphatase.- Multidrug Resistant Gene 1 Product in Human T Cell Subsets: Role of Protein Kinase C Isoforms and Regulation by Cyclosporin A.- Integrins, T Cells, and Autoimmunity.- The Interleukin-2 Receptor: A Target for Immunotherapy.- Section II: T Cell Development.- Lymphocyte Development in Mice Deficient for MHC Class I Expression.- Generation of Mutant Mice Lacking Surface Expression of CD4 or CD8 Gene Targeting.- Alteration of T Cell Lineage Commitment by Expression of a Hybrid CD8/CD4 Transgene.- Differential Involvement of Protein Tyrosine Kinases p56lck and p59fyn in T Cell Development.- Mechanism of Tolerance Induction.- Section III: B Cell Development, Activation, Proliferation, And Differentiation.- B-Lymphocyte Lineage-Committed, IL-7 and Stroma Cell-Reactive Progenitors and Precursors, and Their Differentiation to B Cells.- Regulatory Cells and Cytokines Involved in Primary B Lymphocyte Production.- The Role of IL-7 and Its Receptor in B-Cell Ontogeny.- Role of Contact and Soluble Factors in the Growth and Differentiation of B Cells by Helper T Cell.- B-Cell Activation Mediated by Interactions with Membranes from Helper T Cells.- The Low Affinity IgE Fc Receptor (CD23) Participates in B Cell Activation.- Section IV: Adhesion Molecules: Structure, Regulation and Functions.- T Cell Adhesion Cascades: General Considerations and Illustration with CD31.- Analyses of VLA-4 Structure and Function.- On the Regulation of ?2 Integrins.- Leukocyte-Endothelial Cell Adhesion as an Active, Multi-Step Process: A Combinatorial Mechanism for Specificity and Diversity in Leukocyte Targeting.- Contributors.

General

Imprint: Kluwer Academic / Plenum Publishers
Country of origin: Netherlands
Series: Advances in Experimental Medicine and Biology, v. 323
Release date: November 1992
First published: 1992
Volume editors: Sudhir Gupta • Thomas A. Waldmann
Dimensions: 260mm (L)
Format: Hardcover
Pages: 200
ISBN-13: 978-0-306-44312-1
Categories: Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
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LSN: 0-306-44312-0
Barcode: 9780306443121

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