Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip (Hardcover)

Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

General

Imprint:	Taylor & Francis
Country of origin:	United Kingdom
Series:	Emerging Materials and Technologies
Release date:	July 2022
First published:	2023
Authors:	Sudip Poddar • Bhargab B. Bhattacharya
Dimensions:	234 x 156 x 21mm (L x W x T)
Format:	Hardcover
Pages:	206
ISBN-13:	978-1-03-211380-7
Categories:	Books > Medicine > Nursing & ancillary services > Biomedical engineering > General Books > Professional & Technical > Biochemical engineering > Biotechnology > General
LSN:	1-03-211380-4
Barcode:	9781032113807

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