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Handbook of Animal Models and its Uses in Cancer Research (Hardcover, 1st ed. 2022)
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Handbook of Animal Models and its Uses in Cancer Research (Hardcover, 1st ed. 2022)
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This reference book compiles together different animal models in
cancer research. It provides knowledge and a better understanding
of the advancement of the molecular and cellular mechanisms
associated with the progression, formation, and clinical results of
various types of cancer from the evidence collected from animal
models utilized for cancer research. It discusses animal models for
screening anti-cancer drugs and exploration of gene therapy. It
presents different methods used to construct cancer animal models
and the progress of each animal model in tumor research. The book
also highlights the applications of genetic engineering, including
CRISP/Cas9, in designing and developing animal models for cancer
research. Further, it discusses strategies for modeling animals for
investigating growth, metastasis, tumor-associated inflammation and
microenvironment, cancer stem cells, tumor heterogeneity, and
therapeutic resistance. This book is s a valuable resource for
basic and translational cancer researchers, clinicians, and health
care.
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