The combination of electron microscopy with transmitted light
microscopy (termed correlative light and electron microscopy; CLEM)
has been employed for decades to generate molecular identification
that can be visualized by a dark, electron-dense precipitate. This
new volume of "Methods in Cell Biology" covers many areas of CLEM,
includinga brief history and overview on CLEM methods, imaging of
intermediate stages of meiotic spindle assembly in "C. elegans"
embryos using CLEM, and capturing endocytic segregation events with
HPF-CLEM.
Covers many areas of CLEM by the best international scientists in
the fieldIncludes a brief history and overview on CLEM methods"
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