Diffuse Gastric Cancer (Paperback, 1st ed. 2018)

We live in an era of personalized medicine and the knowledge about pathophysiology of diffuse gastric cancer has had many advances. Thus, the role of this work is to clarify what is new from diagnosis to treatment of this disease in order to treat patients in the most tailored manner as possible. Almost all phase III trials in gastric cancer have been performed without taking in consideration histologic subtypes, i.e. they have disregarded the differences between diffuse gastric cancer and general gastric cancer. However, the clinical practice reveals that diffuse gastric cancer is a completely distinct disease, with an aggressive course and generally worse prognosis. The loss of cohesion between tumor cells due to the loss of E-cadherin synthesis is the critical point on the oncogenesis of diffuse gastric cancer and is at the root of its marked heredity. This book intends to give special attention to Diffuse Gastric Cancer as a particular oncological entity, differentiating it from general gastric cancer, exploring and discussing all its peculiarities, and addressing the basic aspects (pathology and genetics) along with the most recent therapeutic alternatives for this condition.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Release date:	September 2018
First published:	2018
Editors:	Tiago Biachi de Castria • Rodrigo Santa Cruz Guindalini
Dimensions:	235 x 155mm (L x W)
Format:	Paperback
Pages:	81
Edition:	1st ed. 2018
ISBN-13:	978-3-319-95233-8
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Clinical & internal medicine > Gastroenterology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	3-319-95233-1
Barcode:	9783319952338

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