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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Diffuse Gastric Cancer (Paperback, 1st ed. 2018)
Loot Price: R1,506
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Diffuse Gastric Cancer (Paperback, 1st ed. 2018)
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We live in an era of personalized medicine and the knowledge about
pathophysiology of diffuse gastric cancer has had many advances.
Thus, the role of this work is to clarify what is new from
diagnosis to treatment of this disease in order to treat patients
in the most tailored manner as possible. Almost all phase III
trials in gastric cancer have been performed without taking in
consideration histologic subtypes, i.e. they have disregarded the
differences between diffuse gastric cancer and general gastric
cancer. However, the clinical practice reveals that diffuse gastric
cancer is a completely distinct disease, with an aggressive course
and generally worse prognosis. The loss of cohesion between tumor
cells due to the loss of E-cadherin synthesis is the critical point
on the oncogenesis of diffuse gastric cancer and is at the root of
its marked heredity. This book intends to give special attention to
Diffuse Gastric Cancer as a particular oncological entity,
differentiating it from general gastric cancer, exploring and
discussing all its peculiarities, and addressing the basic aspects
(pathology and genetics) along with the most recent therapeutic
alternatives for this condition.
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